Studies of plasma biomarkers for CKD progression

2019

Title Author(s) Publication
Prediction of rapid kidney function decline using machine learning combining blood biomarkers and electronic health record data Girish N. Nadkarni, Fergus Fleming, James R. McCullough, Kinsuk Chauhan, Divya A. Verghese, John C. He, John Quackenbush, Joseph V. Bonventre, Barbara Murphy, Chirag R. Parikh, Michael Donovan, Steven G. Coca bioRxiv
Link: https://www.biorxiv.org/content/10.1101/587774v1
Source: bioRxiv
Theme:Prediction of rapid kidney decline using machine learning
Biomarker(s): sTNFR1, sTNFR1, KIM-1

2018

Title Author(s) Publication
High Baseline Levels of Tumor Necrosis Factor Receptor 1 Are Associated With Progression of Kidney Disease in Indigenous Australians With Diabetes: The eGFR Follow-up Study Elizabeth L.M. Barr, Federica Barzi, Jaquelyne T. Hughes, George Jerums, Wendy E. Hoy, Kerin O’Dea, Graham Jones, Paul D. Lawton, Alex D.H. Brown, Mark Thomas, Elif I. Ekinci, Ashim Sinha, Alan Cass, Richard J. MacIsaac, and Louise J. Maple-Brown Diabetes Care
Link: http://care.diabetesjournals.org/content/41/4/739.long
Source: American Diabetes Association
Theme: Kidney Disease in Indigenous Australians With Diabetes
Biomarker(s): sTNFR1
Title Author(s) Publication
Inflammation and Trajectory of Renal Function in Community- Dwelling Older Adult Shabnam Salimi MD, Michelle D. Shardell PhD, Stephen L. Seliger MD, Stefania Bandinelli MD, Jack M. Guralnik MD, PhD, and Luigi Ferrucci MD, PhD Journal of the American Geriatrics Society
Link: https://onlinelibrary.wiley.com/doi/pdf/10.1111/jgs.15268
Source: Wiley Online Library
Theme: Clinical management of the older adult
Biomarker(s): sTNFR1, sTNFR2
Title Author(s) Publication
Plasma biomarkers improve prediction of diabetic kidney disease in adults with type 1 diabetes over a 12-year follow-up: CACTI study Petter Bjornstad, Laura Pyle, David Z.I. Cherney, Richard J. Johnson, Rachel Sippl, Randy Wong, Marian Rewers, and Janet K. Snell-Bergeon Nephrology Dialysis Transplantation
Link: https://academic.oup.com/ndt/article/33/7/1189/4086527
Source: Oxford Acedemic
Theme: Plasma biomarkers
Biomarker(s): KIM-1
Title Author(s) Publication
Plasma biomarkers are associated with renal outcomes in individuals with APOL1 risk variants Nadkarni GN, Chauhan K, Verghese DA, Parikh CR, Do R, Horowitz CR, Bottinger EP, Coca SG Kidney International
Link: https://www.ncbi.nlm.nih.gov/pubmed/29685497
Source: NCBI
Theme: APOL1
Biomarker(s): sTNFR1, sTNFR2, KIM-1
Title Author(s) Publication
Association of Soluble TNFR-1 Concentrations with Long-Term Decline in Kidney Function: The Multi-Ethnic Study of Atherosclerosis Pavan K. Bhatraju, Leila R. Zelnick, Michael Shlipak, Ronit Katz and Bryan Kestenbaum JASN
Link: https://jasn.asnjournals.org/content/29/11/2713
Source: JASN
Theme: The Multi-Ethnic Study of Atherosclerosis
Biomarker(s): sTNFR1
Title Author(s) Publication
Plasma TNF Receptor Concentrations After Hospitalization with AKI and Long-Term CKD and Mortality Steven Coca, Dennis Moledina, Mark Wurfel, Edward Siew, Amit Garg, Chi-yuan Hsu, James Kaufman, Paul Kimmel, Chirag Parikh ASN Kidney Week
Link: https://www.asn-online.org/education/kidneyweek/2018/program-abstract.aspx?controlId=3018602
Source: ASN
Theme: Long-term CKD
Biomarker(s): sTNFR1, sTNFR2

2017

Title Author(s) Publication
Use of Proteomics To Investigate Kidney Function Decline over 5 Years   Axel C. Carlsson, Erik Ingelsson, Johan Sundström, Juan Jesus Carrero, Stefan Gustafsson, Tobias Feldreich, Markus Stenemo, Anders Larsson, Lars Lind and Johan Ärnlöv CJASN
Link: https://cjasn.asnjournals.org/content/12/8/1226.long
Source: American Society of Nephrology
Theme: Kidney Function
Biomarker(s): sTNFR1, sTNFR2
Title Author(s) Publication
Plasma Biomarkers and Kidney Function Decline in Early and Established Diabetic Kidney Disease Steven G. Coca, Girish N. Nadkarni, Yuan Huang, Dennis G. Moledina, Veena Rao, Jane Zhang, Bart Ferket, Susan T. Crowley, Linda F. Fried and Chirag R. Parikh American Society of Nephrology
Link: https://jasn.asnjournals.org/content/28/9/2786.long
Source: JASN
Theme: Kidney function decline
Biomarker(s): STNFR1, sTNFR2, KIM-1
Title Author(s) Publication
High levels of circulating TNFR1 increase the risk of all‐cause mortality and progression of renal disease in type 2 diabetic nephropathy Gema Fernández‐Juárez, Javier Villacorta Perez, José Luis Luño Fernández, Ernesto Martinez‐Martinez, Victoria Cachofeiro, Vicente Barrio Lucia, Ana M. Tato Ribera, Angel Mendez Abreu, Alfredo Cordon, Jesus Angel Oliva Dominguez, Manuel Praga Terente Nephrology
Link: https://onlinelibrary.wiley.com/doi/pdf/10.1111/nep.12781
Source: Wiley Online Library
Theme: Asian Pacific Society of Nephrology
Biomarker(s): sTNFR1, sTNFR2
Title Author(s) Publication
Association of Circulating Biomarkers (Adrenomedullin, TNFR1, and NT-proBNP) With Renal Function Decline in Patients With Type 2 Diabetes: A French Prospective Cohort Pierre-Jean Saulnier, Elise Gand4, Gilberto Velho, Kamel Mohammedi, Philippe Zaoui8, Mathilde Fraty, Jean Michel Halimi, Ronan Roussel, Stéphanie Ragot and Samy Hadjadj Diabetes Care
Link: http://care.diabetesjournals.org/content/40/3/367.long
Source: American Diabetes Association
Theme: Type 2 Diabetes
Biomarker(s): sTNFR1

2016

Title Author(s) Publication
Increased plasma kidney injury molecule-1 suggests early progressive renal decline in non-proteinuric patients with type 1 diabetes Natalia Nowak, Jan Skupien, Monika A. Niewczas, Masayuki Yamanouchi, Melissa Major, Stephanie Croall, Adam Smiles, James H. Warram, Joseph V. Bonventre, Andrzej S. Krolewski’Correspondence information about the author Andrzej S. Krolewski Kidney International
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848189/
Source: US National Library of Medicine
Theme: Progressively decreasing glomerular filtration rate (GFR)
Biomarker(s): sTNFR1
Title Author(s) Publication
Association of soluble tumor necrosis factor receptors 1 and 2 with nephropathy,  cardiovascular events, and total mortality  in type 2 diabetes Axel C. Carlsson, Carl Johan Östgren , Fredrik H. Nystrom , Toste Länne , Pär Jennersjö, Anders Larsson and Johan Ärnlöv Cardiovascular Diabetology
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770690/
Source: NCBI
Theme: Diabetic kidney disease
Biomarker(s): sTNFR1, sTNFR2
Title Author(s) Publication
The Associations of Blood Kidney Injury Molecule-1 and Neutrophil Gelatinase–Associated Lipocalin with Progression from CKD to ESRD Helen V. Alderson, James P. Ritchie, Sabrina Pagano, Rachel J. Middleton, Menno Pruijm, Nicolas Vuilleumier and Philip A. Kalra CJASN
Link: https://cjasn.asnjournals.org/content/11/12/2141
Source: American Society of Nephrology
Theme: Chronic Kidney Disease
Biomarker(s): KIM-1
Title Author(s) Publication
Increased plasma kidney injury molecule-1 suggests early progressive renal decline in non-proteinuric patients with type 1 diabetes Natalia Nowak, Jan Skupien, Monika A. Niewczas, Masayuki Yamanouchi, Melissa Major, Stephanie Croall, Adam Smiles, James H. Warram, Joseph V. Bonventre, Andrzej S. Krolewski Kidney International
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848189/
Source: US National Library of Medicine
Theme: Progressively decreasing glomerular filtration rate (GFR)
Biomarker(s): KIM-1
Title Author(s) Publication

Elevated plasma tumor necrosis factor- a receptor 2 and resistin are associated with increased incidence of kidney function decline in Chinese adults

Gang Liu, Yueyi Deng, Liang Sun, Xingwang Ye, Pang Yao, Yao Hu, Feijie Wang, Yiwei Ma, Huaixing Li, Yong Liu, Qi Sun

Nutrition and Health of Aging Endocrine
Link: https://link.springer.com/article/10.1007%2Fs12020-015-0807-3
Source: Springer Link
Theme: Kidney function in Chinese adults
Biomarker(s): sTNFR2

2015

Title Author(s) Publication
Biomarkers of rapid chronic kidney disease progression in type 2 diabetes Helen C. Looker, Marco Colombo, Sibylle Hess, Mary J. Brosnan, Bassam Farran, R. Neil Dalton, Max C. Wong, Charles Turner, Colin N.A. Palmer, Everson Nogoceke, Leif Groop, Veikko Salomaa, David B. Dunger, Felix Agakov, Paul M. McKeigue, Helen M. Colhoun
Link: https://www.kidney-international.org/article/S2157-1716(15)32260-7/fulltext
Source: Kidney International
Theme: CKD
Biomarker(s): sTNFR1, sTNFR2, KIM-1

2014

Title Author(s) Publication
Association of Serum Concentration of TNFR1 With All-Cause Mortality in Patients With Type 2 Diabetes and Chronic Kidney Disease: Follow-up of the SURDIAGENE Cohort Pierre-Jean Saulnier Elise Gand4, Stéphanie Ragot, Grégory Ducrocq, Jean-Michel Halimi9,10, Charlotte Hulin-Delmotte, Pierre Llaty, David Montaigne, Vincent Rigalleau15,16, Ronan Roussel, Gilberto Velho, Philippe Sosner Philippe Zaoui, Samy Hadjadj, for the SURDIAGENE Study Group Diabetes Care
Link: http://care.diabetesjournals.org/content/37/5/1425.long
Source: American Diabetes Association
Theme: Type 2 Diabetes and Chronic Kidney Disease
Biomarker(s): sTNFR1
Title Author(s) Publication
Blood Kidney Injury Molecule-1 Is a Biomarker of Acute and Chronic Kidney Injury and Predicts Progression to ESRD in Type I Diabetes Venkata S. Sabbisetti, Sushrut S. Waikar,Daniel J. Antoine, Adam Smiles,Chang Wang, Abinaya Ravisankar,Kazumi Ito, Sahil Sharma,Swetha Ramadesikan, Michelle Lee, Rebeccah Briskin, Philip L. De Jager, Thanh Thu Ngo, Mark Radlinski, James W. Dear, Kevin B. Park, Rebecca Betensky, Andrzej S. Krolewski, and Joseph V. Bonventre JASN
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178434/
Source: NCBI
Theme: ESRD
Biomarker(s): KIM-1
Title Author(s) Publication
Elevation of circulating TNF receptors 1 and 2 increases the risk of end-stage renal disease in American Indians with type 2 diabetes MEDA E. Pavkov, MD, PHD, Robert G. Nelson, MD, PHD, William C. Knowler, MD, DRPH, Yiling Cheng, MD,1 Andrzej S. Krolewski, MD, PHD, and Monika A. Niewczas, MD, PHD Kidney International
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382420/
Source: US National Library of Medicine
Theme: End-stage renal disease in American Indians
Biomarker(s): sTNFR1, sTNFR2
Title Author(s) Publication
Early Progressive Renal Decline Precedes the Onset of Microalbuminuria and Its Progression to Macroalbuminuria Andrzej S. Krolewski, Monika A. Niewczas, Jan Skupien, Tomhito Gohda,Adam Smiles, Jon H. Eckfeldt, Alessandro Doria, and James H. Warram Diabetes Care
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867993/
Source: NCBI
Theme: Renal decline
Biomarker(s): sTNFR1

2012

Title Author(s) Publication
Circulating TNF Receptors 1 and 2 Predict Stage 3 CKD in Type 1 Diabetes Tomohito Gohda, Monika A. Niewczas, Linda H. Ficociello, William H. Walker, Jan Skupien, Florencia Rosetti, Xavier Cullere, Amanda C. Johnson, Gordon Crabtree, Adam M. Smiles, Tanya N. Mayadas, James H. Warram, and Andrzej S. Krolewski JASN
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294299/
Source: NCBI
Theme: ESRD
Biomarker(s): sTNFR1, sTNFR2
Title Author(s) Publication
Circulating TNF Receptors 1 and 2 Predict ESRD in Type 2 Diabetes Monika A. Niewczas, Tomohito Gohda, Jan Skupien, Adam M. Smiles, William H. Walker, Florencia Rosetti, Xavier Cullere John H. Eckfeldt, Alessandro Doria, Tanya N. Mayadas, James H. Warram, and Andrzej S. Krolewski JASN
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294310/
Source: US National Library of Medicine
Theme: Predict ESRD in Type 2 Diabetes
Biomarker(s): sTNFR1, sTNFR2

2011

Title Author(s) Publication
Markers of inflammation predict the long-term risk of developing chronic kidney disease: a population-based cohort study Anoop Shankar, Liping Sun, Barbara E.K. Klein, Kristine E. Lee, Paul Muntner, F. Nieto Javier, Michael Y. Tsai, Karen J. Cruickshanks, Carla R. Schubert, Peter C. Brazy, Josef Coresh, Ronald Klein Kidney International
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260339/
Source: US National Library of Medicine
Theme: Markers of inflammation
Biomarker(s): sTNFR2