Studies supporting utility and impact of KidneyIntelX

2020

Title Author(s) Publication
Evaluation of Payer Budget Impact Associated with the Use of Artificial Intelligence in vitro Diagnostic, KidneyIntelX™, to Modify DKD Progression Manasi Datar PhD, William Burchenal, BA, Michael Donovan PhD, MD, Steve Coca, DO, O. James Sterling, MBA, Elaine Wang, BA, Thomas F. Goss, PharmD Podium Presentation at NKF Spring Clinical Meeting
Link: Evaluation of Payer Budget Impact Associated with the Use of Artificial Intelligence in vitro Diagnostic, KidneyIntelX™
Source: Presentation delivered by Thomas Goss, Pharm D, Snr Vice President, Boston Healthcare Associates on 26 March 2020
Theme: Healthcare economics
Title Author(s) Publication
Derivation and validation of a machine learning risk score using biomarker and electronic patient data to predict rapid progression of diabetic kidney disease Lili Chan, Girish N. Nadkarni, Fergus Fleming, James R. McCullough, Patti Connolly, Gohar Mosoyan, Fadi El Salem, Michael W. Kattan, Joseph A. Vassalotti, Barbara Murphy, Michael J. Donovan, Steven G. Coca, Scott Damrauer MedRxiv
Link: https://www.medrxiv.org/content/10.1101/2020.06.01.20119552v3
Source:MedRxiv
Theme: KidneyIntelX Validation Study
Title Author(s) Publication
Initial validation of a machine learning-derived prognostic test (KidneyIntelX) integrating biomarkers and electronic health record data to predict longitudinal kidney outcomes Kinsuk Chauhan, Girish N. Nadkarni, Fergus Fleming, James McCullough, Cijiang J. He, John Quackenbush, Barbara Murphy, Michael J. Donovan, Steven G. Coca and Joseph V. Bonventre Kidney360
Link: https://kidney360.asnjournals.org/content/early/2020/06/29/KID.0002252020
Source:Kidney360
Theme: KidneyIntelX Validation Study

2019

Title Author(s) Publication
Nephrology consultation and mortality in people with stage 4 chronic kidney disease: a population-based study Ping Liu PhD, Robert R. Quinn MD PhD, Mohammad Ehsanul Karim PhD, Aminu Bello MD PhD, Helen Tam-Tham PhD, Robert Weaver MSc, Paul E. Ronksley PhD, Hude Quan PhD, Giovanni F.M. Strippoli MD PhD, Braden Manns MD PhD, Brenda R. Hemmelgarn MD PhD, Marcello Tonelli MD SM, Pietro Ravani MD PhD CMAJ
Link: http://www.cmaj.ca/content/191/10/E274
Source: CMAJ
Theme: Stage 4 CKD
Title Author(s) Publication
You Are Just Now Telling Us About This? African American Perspectives of Testing for Genetic Susceptibility to Kidney Disease Ebele M. Umeukeje, Bessie A. Young, Stephanie M. Fullerton, Kerri Cavanaugh, Delia Owens, James G. Wilson, Wylie Burke and Erika Blacksher JASN
Link: https://www.asn-online.org/education/kidneyweek/2018/program-abstract.aspx?controlId=3018602
Source: ASN
Theme: Testing for genetic susceptibility to kidney disease
Title Author(s) Publication
Blood Pressure Goals in Patients with Chronic Kidney Disease Alex R. Chang, Meghan Lóser, Rakesh Malhotra and Lawrence J. Appel CJASN
Link: https://www.ncbi.nlm.nih.gov/pubmed/30455322
Source: NCBI
Theme: CKD

2018

Title Author(s) Publication
Canagliflozin and renal outcomes in type 2 diabetes: results from the CANVAS Program randomised clinical trials Vlado Perkovic, Dick de Zeeuw, Kenneth W Mahaffey, Greg Fulcher, Ngozi Erondu, Wayne Shaw, Terrance D Barrett, Michele Weidner-Wells, Hsiaowei Deng, David R Matthews, Bruce Neal The Lancet Diabetes & Endocrinology
Link: https://www.ncbi.nlm.nih.gov/pubmed/29937267
Source: NCBI
Theme: Type 2 diabetes
Title Author(s) Publication
Empagliflozin and Kidney Function Decline in Patients with Type 2 Diabetes: A Slope Analysis from the EMPA-REG OUTCOME Trial Christoph Wanner, Hiddo J.L. Heerspink, Bernard Zinman, Silvio E. Inzucchi, Audrey Koitka-Weber, Michaela Mattheus, Stefan Hantel, Hans-Juergen Woerle, Uli C. Broedl, Maximilian von Eynatten, Per-Henrik Groop and on behalf of the EMPA-REG OUTCOME Investigators JASN
Link: https://www.ncbi.nlm.nih.gov/pubmed/30314978
Source: NCBI
Theme: Type 2 diabetes
Title Author(s) Publication
Management of Traditional Cardiovascular Risk Factors in CKD: What Are the Data? L. Parker Gregg and S. Susan Hedayati AJKD
Link: https://www.ncbi.nlm.nih.gov/pubmed/29478869
Source: NCBI
Theme: CKD
Title Author(s) Publication
Effect of 2 Clinical Decision Support Strategies on Chronic Kidney Disease Outcomes in Primary Care A Cluster Randomized Trial Jennifer K. Carroll, MD, MPH; Gerald Pulver, PhD; L. Miriam Dickinson, PhD JAMA Network Open
Link: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2709713
Source: JAMA Network Open
Theme: CKD
Title Author(s) Publication
Cost-effectiveness of multidisciplinary care in mild to moderate chronic kidney disease in the United States: A modeling study Eugene Lin, Glenn M. Chertow, Brandon Yan, Elizabeth Malcolm, Jeremy D. Goldhaber-Fiebert PLOS Medicine
Link: https://www.ncbi.nlm.nih.gov/pubmed/29584720
Source: NCBI
Theme: CKD
Title Author(s) Publication
SGLT2 inhibitors and mechanisms of cardiovascular benefit: a state-of-the-art review Subodh Verma & John J. V. McMurray Diabetologia
Link: https://www.ncbi.nlm.nih.gov/pubmed/30132036
Source: NCBI
Theme: SGLT2 inhibitors

2017

Title Author(s) Publication
Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes Bruce Neal, M.B., Ch.B., Ph.D., Vlado Perkovic, M.B., B.S., Ph.D., Kenneth W. Mahaffey, M.D., Dick de Zeeuw, M.D., Ph.D., Greg Fulcher, M.D., Ngozi Erondu, M.D., Ph.D., Wayne Shaw, D.S.L., Gordon Law, Ph.D., Mehul Desai, M.D., and David R. Matthews, D.Phil., B.M., B.Ch. for the CANVAS Program Collaborative Group* The New England Journal of Medicine
Link: https://www.nejm.org/doi/full/10.1056/NEJMoa1611925
Source: The New England Journal of Medicine
Theme: Type 2 diabetes

2016

Title Author(s) Publication
Empagliflozin and Progression of Kidney Disease in Type 2 Diabetes Christoph Wanner, M.D., Silvio E. Inzucchi, M.D., John M. Lachin, Sc.D., David Fitchett, M.D., Maximilian von Eynatten, M.D., Michaela Mattheus, Dipl. Biomath., Odd Erik Johansen, M.D., Ph.D., Hans J. Woerle, M.D., Uli C. Broedl, M.D., and Bernard Zinman, M.D. for the EMPA-REG OUTCOME Investigators* The New England Journal of Medicine
Link: https://www.nejm.org/doi/full/10.1056/NEJMoa1515920
Source: The New England Journal of Medicine
Theme: Type 2 diabetes

2015

Title Author(s) Publication
Multidisciplinary care in patients with chronic kidney disease: A systematic review and meta-analysis Su-MingWang, Lien-Cheng Hsiao, I-Wen Ting, Tung-Min Yu, Chih-Chia Liang, Huey-Liang Kuo, Chiz-Tzung Chang, Jiung-Hsiun Liu, Che-Yi Chou, Chiu-Ching Huang European Journal of Internal Medicine
Link: https://www.ncbi.nlm.nih.gov/pubmed/26186813
Source: NCBI
Theme: CKD

2014

Title Author(s) Publication
Early referral to specialist nephrology services for preventing the progression to end-stage kidney disease Smart NA, Dieberg G, Ladhani M, Titus T Cochrane Library
Link: https://www.ncbi.nlm.nih.gov/pubmed/24938824
Source: NCBI
Theme: End-stage kidney disease
Title Author(s) Publication
Primary Care Detection of Chronic Kidney Disease in Adults with Type-2 Diabetes: The ADD-CKD Study (Awareness, Detection and Drug Therapy in Type 2 Diabetes and Chronic Kidney Disease) Lynda A. Szczech, Rebecca C. Stewart, Hsu-Lin Su, Richard J. DeLoskey, Brad C. Astor, Chester H. Fox, Peter A. McCullough, Joseph A. Vassalotti PLOS ONE
Link: https://www.ncbi.nlm.nih.gov/pubmed/25427285
Source: NCBI
Theme: CKD, Type 2 Diabetes